**½/**** Image A- Sound A Extras B
starring Bill Murray, Molly Shannon, Elena Franklin, Chris Elliott
screenplay by Marc Hyman
directed by Bobby Farrelly, Peter Farrelly, Piet Kroon and Tom Sito
by Walter Chaw If the devil is in the details, so, in Osmosis Jones, is most of the humour. It is one part Farrelly Brothers biological comedy and one part Piet Kroon and Tom Sito (late of The Iron Giant) animated genius; that the balance of the film is heavily in favour of the latter speaks to rare good thinkin' from the Hollywood brain trust. The live-action part stars Bill Murray as the slovenly Frank--Murray out-repulses co-star Chris Elliot, which means that he is very possibly the most disgusting human ever captured on film. The animation side features the voice of Chris Rock as the titular Osmosis Jones, a white blood cell cop who, after a controversial stomach evacuation, is busted down to mouth duty. If you're not sure what "mouth duty" entails--it's bad. When Frank is invaded by an evil virus named Thrax (Laurence Fishburne), Osmosis gets one last chance to make good, paired with a blustering blunderbuss of a timed flu capsule named Drix (David Hyde Pierce).